KASSIS LABORATORY
PUBLICATION LIST
Sgouros G, Knox SJ, Joiner MC, Morgan WF, Kassis AI.
MIRD continuing education: Bystander and low–dose-rate effects: are these
relevant to radionuclide therapy? J Nucl Med 2007; 48:1683-91.
Singh A, Chen K,
Adelstein SJ, Kassis AI. Synthesis of coumarin–polyamine-based molecular probe for
the detection of hydroxyl radicals generated by gamma radiation. Radiat Res
2007; 168:233-42.
Wang K,
Kirichian AM, Al Aowad AF, Adelstein SJ, Kassis AI. Evaluation of chemical, physical,
and biologic properties of tumor-targeting radioiodinated quinazolinone
derivative.
Bioconjugate Chem 2007; 18:754-64.
Chen K, Al
Aowad AF, Adelstein SJ, Kassis AI. Molecular-docking-guided design, synthesis, and biologic
evaluation of radioiodinated quinazolinone prodrugs. J Med Chem 2007;
50:663-73.
Pospisil P, Wang K, Al Aowad AF, Iyer LK, Adelstein
SJ, Kassis AI. Computational modeling and experimental
evaluation of a novel prodrug for targeting the extracellular space of prostate
tumors. Cancer Res 2007; 67:2197-205.
Yasui LS, Chen K, Wang K, Jones TP,
Caldwell J, Guse D, Kassis AI. Using Hoechst 33342 to target
radioactivity to the cell nucleus. Radiat Res 2007; 167:167-75.
Urashima T,
Nagasawa H, Wang K, Adelstein SJ, Little JB, Kassis AI. Induction of apoptosis in human
tumor cells after exposure to Auger electrons: comparison with g-ray
exposure. Nucl Med Biol 2006; 33:1055-63.
Chen K, Wang K,
Kirichian AM, Al Aowad AF, Iyer LK, Adelstein SJ, Kassis AI. In silico design, synthesis, and biological evaluation of
radioiodinated quinazolinone derivatives for alkaline phosphatase–mediated
cancer diagnosis and therapy. Mol Cancer Ther 2006; 5:3001-13.
Balagurumoorthy P, Chen K, Bash RC, Adelstein SJ,
Kassis AI. Mechanisms underlying production of double-strand breaks in plasmid
DNA after decay of 125I-Hoechst. Radiat Res
2006; 166:333-44.
Pospisil P,
Iyer LK, Adelstein SJ, Kassis AI. A combined approach to data mining
of textual and structured data to identify cancer-related targets. BMC Bioinformatics 2006; 7:354.
Wang K, Adelstein SJ, Kassis AI. Radiotracer-based
method for determining water solubility of highly insoluble compounds. J
Labelled Comp Radiopharm 2006; 49:773-88.
Kishikawa H, Wang K, Adelstein SJ, Kassis AI.
Inhibitory and stimulatory bystander effects are differentially induced by
iodine-125 and iodine-123. Radiat Res
2006; 165:688-94.
Wang K, Chen K, Kassis AI.
Technol
2006; 41:622-7.
Barcellos-Hoff, MH, Chaudhry MA, De Veaux L, Geard C,
Kadhim M, Kassis A, Little JB, Maissen A, Mitchel R, Morgan BF, Mosse I, Müller
W, Newman DJ, Nikjoo H, Niwa O, Prise K, Redpath L, Sáfrány G, Sakai K,
Schofield P, Resat MS, Springer D, Stanbridge E, Suzuki K, Waker T, Wright EG,
Yuan Z-M, Quinn J, Rainbow A, Rollo D, Seymour C, Mothersill C, Boreham D.
Meeting report: Radiation-induced genomic instability and bystander effects;
implications for evolutionary biology, report on an international workshop on
radiation-induced low-dose effects held at McMaster University in Hamilton,
Ontario, Canada, October 28–November 1, 2004. Radiat Res 2005; 163:473-6.
Kassis AI. Radiotargeting agents
for cancer therapy. Expert Opin Drug Deliv 2005; 2:981-91.
Kassis AI, Adelstein SJ. Radiobiologic
principles in radionuclide therapy. J Nucl Med 2005; 46(Suppl 1):4S-12S.
Chen K,
Adelstein SJ, Kassis AI. (2E)-2-(3,5-dimethoxyphenyl)-3-(4-ethoxy-3-iodophenyl)acrylic
acid. Acta Crystallogr 2005; E61:o3517–o3519.
Safaie Semnani E, Wang K, Adelstein SJ, Kassis AI. 5-[123I/125I]iodo-2’-deoxyuridine in metastatic lung cancer: radiopharmaceutical formulation affects targeting. J Nucl Med 2005; 46:800-6.
Kassis AI. The amazing world of
Auger electrons. Int J Radiat Biol 2004; 80:789-803.
Kassis AI. In vivo
validation of the bystander effect. Hum Exp Toxicol 2004; 23:71-3.
Kassis AI,
Kirichian AM, Wang K, Safaie Semnani E, Adelstein SJ. Therapeutic potential of 5-[125I]iodo-2’-deoxyuridine and methotrexate in the treatment of
advanced neoplastic meningitis. Int J Radiat Biol 2004; 80:941-6.
Chen K,
Adelstein SJ, Kassis AI. Molecular
simulation of ligand-binding with DNA: implications for 125I-labeled
pharmaceutical design. Int J Radiat Biol 2004; 80:921-6.
Urashima T,
Wang K, Adelstein SJ, Kassis AI. Activation of diverse pathways to
apoptosis by 125IdUrd and g-photon exposure. Int J Radiat
Biol 2004; 80:867-74.
Chen K,
Adelstein SJ, Kassis AI. Molecular
modeling of the interaction of iodinated Hoechst analogs with DNA: implications
for new radiopharmaceutical design. J Mol Struct (Theochem)
2004; 711:49-56.
Kassis AI. In-vivo validation of the bystander effect. BELLE Newslett
2003; 11(3):10-2.
Bodei L, Kassis AI, Adelstein SJ, Mariani G.
Radionuclide therapy with iodine-125 and other Auger-electron-emitting
radionuclides: experimental models and clinical applications [update]. Cancer
Biother Radiopharm 2003; 18:861-77.
Adelstein SJ, Kassis AI, Bodei L, Mariani G.
Radiotoxicity of iodine-125 and other Auger-electron-emitting radionuclides:
background to therapy [update]. Cancer Biother Radiopharm 2003; 18:301-16.
Kassis AI. Invited commentary: Cancer therapy with
Auger electrons: are we almost there? J Nucl Med 2003; 44:1479-81.
Kassis AI, Adelstein SJ. Considerations
in the selection of radionuclides for cancer therapy. In: Welch MJ,
Redvanly CS, eds. Handbook of radiopharmaceuticals: radiochemistry and
applications.
Kassis AI. Radiobiology aspects and
radionuclide selection criteria in cancer therapy. In: Zaidi H, Sgouros
G, eds. Therapeutic applications of Monte Carlo calculations in nuclear
medicine.
Xue LY,
Ho N,
Harapanhalli RS, Dahman BA, Chen K, Wang K, Adelstein SJ, Kassis AI. Synthesis and biologic
evaluation of a radioiodinated quinazolinone derivative for enzyme-mediated
insolubilization therapy. Bioconjugate Chem 2002; 13:357-64.
Kundra V,
Mannting F, Jones AG, Kassis AI. Noninvasive monitoring of somatostatin receptor type 2
chimeric gene transfer. J Nucl Med 2002; 43:406-12.
Ho N, Tumeh PC, Kassis AI. Synthesis
and biologic studies of iodinated (125I/127I) ethidium.
Nucl Med Biol 2001; 28:983-90.
Walicka MA, Adelstein SJ, Kassis AI. Chemical
modification of 5-[125I]iodo-2'-deoxyuridine
toxicity in mammalian cells in vitro.
Int J Radiat Biol 2001; 77:625-30.
Mariani G, Bodei L, Adelstein SJ, Kassis AI. Invited
commentary: Emerging roles for radiometabolic therapy of tumors based on Auger
electron emission. J Nucl Med 2000; 41:1519-21.
Kassis AI,
Dahman BA, Adelstein SJ. In vivo therapy of neoplastic
meningitis with methotrexate and 5-[125I]iodo-2'-deoxyuridine.
Acta Oncol 2000; 39:731-7.
Kassis AI, Walicka MA, Adelstein SJ. Double-strand
break yield following 125I decay: effects of DNA conformation. Acta Oncol 2000; 39:721-6.
Walicka MA, Ding Y, Adelstein SJ, Kassis AI. Toxicity
of DNA-incorporated iodine-125: quantifying the direct and indirect effects. Radiat
Res 2000; 154:326-30. Erratum, Radiat Res 2000; 154:608.
Walicka MA,
Ding Y, Adelstein SJ, Kassis AI. Morphological transformation of C3H
10T1/2 cells by 99mTc-Cardiolite. J Nucl Med
2000; 41:1545-51.
Walicka MA,
Ding Y, Roy AM, Harapanhalli RS, Adelstein SJ, Kassis AI. Cytotoxicity of [125I]iodoHoechst 33342: contribution of scavengeable effects. Int J Radiat Biol 1999; 75:1579-87.
Kassis AI,
Harapanhalli RS, Adelstein SJ.
Kassis AI, Harapanhalli RS,
Adelstein SJ.
Comparison of strand breaks in plasmid DNA after positional changes of
Auger-electron-emitting iodine-125. Radiat Res 1999;
151:167-76.
Maulik G, Kassis AI, Savvides P, Makrigiorgos GM.
Fluoresceinated phosphoethanolamine for flow-cytometric measurement of lipid
peroxidation. Free Radic Biol Med 1998; 25:645-53.
Walicka MA, Vaidyanathan G, Zalutsky MR, Adelstein
SJ, Kassis AI. Survival and DNA damage in Chinese hamster V79 cells exposed to
alpha particles emitted by DNA-incorporated astatine-211. Radiat
Res 1998; 150:263-8.
Kassis AI, Wen PY, Van den Abbeele AD,
Baranowska-Kortylewicz J, Makrigiorgos GM, Metz KR, Matalka KZ, Cook CU, Sahu
SK, Black PMcL, Adelstein SJ. 5-[125I]iodo-2'-deoxyuridine
in the radiotherapy of brain tumors in rats. J Nucl Med
1998; 39:1148-54.
Harapanhalli
RS, Roy AM, Adelstein SJ, Kassis AI. [125I/127I/131I]iodorhodamine: synthesis, cellular localization, and
biodistribution in athymic mice bearing human tumor xenografts and comparison
with [99mTc]hexakis(2-methoxyisobutylisonitrile). J
Med Chem 1998; 41:2111-7.
Harapanhalli RS, Matalka KZ, Jones PL, Mahmood A,
Adelstein SJ, Kassis AI. Lysine-directed conjugation of ethidium homodimer to
B72.3 antibody: retention of immunoreactivity but altered tumor targeting. Nucl Med Biol 1998; 25:267-78.
Chakrabarti S, Kassis AI, Slayter
HS, Bump EA,
Walicka MA,
Adelstein SJ, Kassis AI. Indirect
mechanisms contribute to biological effects produced by decay of
DNA-incorporated iodine-125 in mammalian cells in vitro: clonogenic
survival. Radiat Res 1998; 149:142-6.
Walicka MA, Adelstein SJ, Kassis AI. Indirect
mechanisms contribute to biological effects produced by decay of
DNA-incorporated iodine-125 in mammalian cells in vitro: double-strand
breaks. Radiat Res 1998; 149:134-41.
Harapanhalli RS, Matalka KZ, Jones PL, Mahmood A,
Adelstein SJ, Kassis AI. Lysine-directed conjugation of ethidium homodimer to
B72.3 mAb: retention of immunoreactivity and altered tumor targeting. Radiochim Acta 1997; 79:77-82.
Harapanhalli RS, Adelstein SJ,
Kassis AI.
Site-specific conjugation of ethidium homodimer to B72.3 mAb: retention of
immunoreactivity, isoelectric point and in
vivo tumor targeting. Radiochim Acta 1997; 79:73-6.
Sahu SK, Wen PYC, Foulon CF, Nagel JS, Black PMcL,
Adelstein SJ, Kassis AI. Intrathecal 5-[125I]iodo-2'-deoxyuridine
in a rat model of leptomeningeal metastases. J Nucl Med 1997; 38:386-90.
Sahu SK, Kortylewicz ZP,
Baranowska-Kortylewicz J, Taube RA, Adelstein SJ, Kassis AI.
Makrigiorgos GM, Kassis AI, Mahmood A, Bump EA,
Savvides P. Novel fluorescein-based flow-cytometric method for detection of
lipid peroxidation. Free Radic Biol Med 1997; 22:93-100.
Kassis AI as workshop participant. In: Feinendegen
LE, McClure JJ, eds. Workshop on alpha-emitters for medical therapy,
Kassis AI, Adelstein SJ, Mariani G.
Radiolabeled nucleoside analogs in cancer diagnosis and therapy. Q J Nucl Med 1996; 40:301-19.
Mariani G, Di
Sacco S, Bonini R, Di Luca L, Buralli S, Bonora D, Ricci S, Baranowska-Kortylewicz
J, Adelstein SJ, Falcone A, Kassis AI. Biochemical modulation by 5-fluorouracil and l-folinic acid
of tumor uptake of intra-arterial 5-[123I]iodo-2'-deoxyuridine
in patients with liver metastases from colorectal cancer. Acta
Oncol 1996; 35:941-5.
Kassis AI, Adelstein SJ. 5-[125I]iodo-2'-deoxyuridine in the radiotherapy of solid CNS
tumors in rats. Acta Oncol 1996; 35:935-9.
Adelstein SJ, Kassis AI.
Makrigiorgos GM, Bump E, Kassis AI. Molecular
dosimetry of radiation induced free radicals using a chromatin-incorporated
fluorescent molecule. In: Giakoumakis E, Anagnostakis MJ, Petropoulos NP, eds.
Proceedings First Mediter Conf Radiat Prot, Athens, Greece, 1994.
Mariani G, Di
Sacco S, Volterrani D, Di Luca L, Buralli S, Di Stefano R,
Baranowska-Kortylewicz J, Bonora D, Matteucci F, Ricci S, Bellina CR, Falcone
A, Salvadori PA, Mosca F, Adelstein SJ, Kassis AI. Tumor targeting by intra-arterial
infusion of 5-[123I]-iodo-2'-deoxyuridine in patients with liver
metastases from colorectal cancer. J Nucl Med 1996; 37(4, suppl):22S-25S.
Kassis AI, Tumeh SS, Wen PYC, Baranowska-Kortylewicz
J, Van den Abbeele AD, Zimmerman RE, Carvalho PA, Garada BM, DeSisto WC, Bailey
NO, Castronovo FP Jr, Mariani G, Black PMcL, Adelstein SJ. Intratumoral
administration of 5-[123I]iodo-2'-deoxyuridine
in a patient with a brain tumor. J Nucl Med 1996; 37(4, suppl):19S-22S.
Mariani G, Collecchi P, Baldassarri S, Di Luca L,
Buralli S, Fontanini G, Baranowska-Kortylewicz J, Adelstein SJ, Kassis AI.
Tumor uptake and mitotic activity pattern of 5-[125I]iodo-2'-deoxyuridine after intravesical infusion in
patients with bladder cancer. J Nucl Med 1996; 37(4, suppl):16S-19S.
Kassis AI, Adelstein SJ. Preclinical animal studies
with radioiododeoxyuridine. J Nucl Med 1996; 37(4, suppl):10S-12S.
Foulon CF, Adelstein SJ, Kassis AI. Kit formulation
for the preparation of radiolabeled
iododeoxyuridine
by demetallation. J Nucl Med 1996; 37(4, suppl):1S-3S.
Kassis AI, Adelstein SJ. Preface to Radiolabeled
IUdr, proceedings of symposium on clinical applications of radiolabeled IUdR. J Nucl Med 1996; 37(4, suppl).
Harapanhalli RS, McLaughlin LW,
Howell RW, Rao DV, Adelstein SJ, Kassis AI. [125I/127I]iodoHoechst 33342: synthesis, DNA binding, and
biodistribution. J Med Chem 1996; 39:4804-9.
Chakrabarti S, Mahmood A, Kassis AI, Bump EA, Jones
AG, Makrigiorgos GM. Generation of hydroxyl radicals by nucleohistone-bound
metal–adriamycin complexes. Free Radic Res 1996; 25:207-20.
Foulon CF, Adelstein SJ, Kassis AI. One-step synthesis of radioiodinated biotin derivatives. Bioorg Med Chem Lett 1996; 6:779-84.
Chakrabarti S, Makrigiorgos GM, O'Brien K, Bump E,
Kassis AI. Measurement of hydroxyl radicals catalyzed in the immediate vicinity
of DNA by metal–bleomycin complexes. Free Radic Biol Med 1996; 20:777-83.
Kassis AI,
Jones PL, Matalka KZ, Adelstein SJ. Antibody-dependent signal
amplification in tumor xenografts after pretreatment with biotinylated
monoclonal antibody and avidin or streptavidin. J Nucl Med 1996; 37:343-52.
Van den Abbeele AD, Tutrone RF, Berman RM,
Baranowska-Kortylewicz J, Barclay PD, Richie JP, Adelstein SJ, Kassis AI. Tumor-targeting potential of radioiodinated iododeoxyuridine in
bladder cancer. J Nucl Med 1996; 37:315-20.
Muto MG, Kassis AI. Monoclonal antibodies used in the
detection and treatment of epithelial ovarian cancer. Cancer
1995; 76:2016-27.
Adelstein SJ, Kassis AI. Radiobiology.
In: Wagner HN Jr, Szabo Z, Buchanan JW, eds. Principles of nuclear medicine. Second edition.
Foulon CF,
Zhang YZ, Adelstein SJ, Kassis AI. Instantaneous preparation of radiolabeled
5-iodo-2'-deoxyuridine. Appl Radiat Isot 1995; 46:1039-46.
Gangopadhyay A,
Makrigiorgos GM, Bump E, Huang C,
Baranowska-Kortylewicz J, Kassis AI. A fluorimetric method
for the detection of copper-mediated hydroxyl free radicals in the immediate
proximity of DNA. Free Radic Biol Med 1995; 18:669-78.
Sahu SK, Kassis AI, Makrigiorgos GM,
Baranowska-Kortylewicz J, Adelstein SJ. The effects of indium-111 decay on
pBR322 DNA. Radiat Res 1995; 141:193-8.
Mariani G, Di
Sacco S, Volterrani D, Matteucci F, Di Luca L, Buralli S,
Baranowska-Kortylewicz J, Di Stefano R, Ricci S, Bellina CR, Falcone A,
Salvadori PA, Mosca F, Adelstein SJ, Kassis AI. Tumor targeting with 5-[123I]iodo-2'-deoxyuridine infused into the hepatic artery of
patients with liver metastases from colorectal cancer. J Nucl Biol Med 1994;
38:265-6.
Kassis AI. Toxicity and therapeutic
effects of low-energy electrons. Nucl Instr Meth Phys Res B 1994;
87:279-84.
Charlton DE,
Kassis AI, Adelstein SJ. A
comparison of experimental and calculated survival curves for V79 cells grown
as monolayers or in suspension exposed to alpha irradiation from 212Bi
distributed in the growth medium. Radiat Prot Dosimetry 1994;
52:311-5.
Kortylewicz ZP,
Baranowska-Kortylewicz J, Adelstein SJ,
Howell RW, Kassis AI, Adelstein SJ,
Rao DV, Wright HA,
Makrigiorgos GM, Bump E, Huang C,
Baranowska-Kortylewicz J, Kassis AI. Accessibility of nucleic acid-complexed
biomolecules to hydroxyl radicals correlates with their conformation: a
fluorescence polarization spectroscopy study. Int J Radiat
Biol 1994; 66:247-57.
Gangopadhyay A,
Van den Abbeele AD, Kassis AI. Modification of mouse IgG isoelectric point following radioiodination. Antibody Immunoconj Radiophar 1994; 7:171-8.
Gangopadhyay A,
Makrigiorgos
GM, Folkard M, Huang C, Bump E, Baranowska-Kortylewicz J, Sahu SK, Michael BD,
Kassis AI. Quantification of radiation-induced hydroxyl radicals within
nucleohistones using a molecular fluorescent probe. Radiat Res
1994; 138:177-85.
Mariani G, Di
Sacco G, Matteucci F, Volterrani D, Baranowska-Kortylewicz J, Ricci S, Di
Stefano R, Troiani R, Di Luca L, Falcone A, Bellina CR, Salvadori PA, Conte PF,
Sicari A, Mosca F, Adelstein SJ, Kassis AI. Intra-arterial infusion of 5-[123I]iodo-2'-deoxyuridine in patients with liver metastases from
colon cancer. J Nucl Biol Med 1993; 37:157-8.
Mariani G, Giuliani L, Baranowska-Kortylewicz J,
Collecchi P, Meucci G, Di Luca L, Viacava P, Van den Abbeele AD, Bevilacqua G,
Salvadori PA, Adelstein SJ, Kassis AI. Intratumoral injection of 5-[125I]iodo-2'-deoxyuridine in patients with breast cancer. In:
Hofer R, Bergmann H, Sinzinger H, eds. Radioactive isotopes in clinical
medicine and research. Stuttgart: Schattauer Verlag, 1993:188-93.
Weber DA,
Kassis AI. Co-editors preface. Special Supplement of Medical Physics on radiolabeled antibody tumor
dosimetry. Med Phys 1993; 20:497.
Kassis AI, Adelstein SJ. Therapeutic
potential of internally administered radionuclides. In: Black PMcL,
Schoene WC, Lampson LA, eds. Contemporary issues in neurological surgery.
Astrocytomas: diagnosis, treatment, and biology.
Speidel MT, Holmquist B, Kassis AI, Humm JL, Berman
RM, Atcher RW, Hines JJ, Macklis RM. Morphological, biochemical, and molecular
changes in endothelial cells following alpha-particle irradiation. Radiat Res 1993; 136:373-81.
Mariani G, Collecchi P, Giuliani L,
Baranowska-Kortylewicz J, Di Luca L, Meucci G, Viacava P, Van den Abbeele AD,
Salvadori PA, Di Sacco S, Adelstein SJ, Bevilacqua G, Kassis AI. Tumor
targeting potential and metabolism of 5-[125I]iodo-2'-deoxyuridine
injected intratumorally in patients with breast cancer. Ann
NY Acad Sci 1993; 698:204-11.
Baranowska-Kortylewicz J, Kassis AI. Labeling of
sulfhydryl groups in intact mammalian cells with coumarins. Bioconjugate Chem 1993; 4:305-7.
Baranowska-Kortylewicz J, Kassis AI. Labeling of immunoglobulins
with bifunctional, sulfhydryl-selective, and photoreactive coumarins. Bioconjugate Chem 1993; 4:300-4.
Mariani G, Cei A, Collecchi P, Baranowska-Kortylewicz
J, Van den Abbeele AD, Di Luca L, Di Stefano R, Viacava P, Ferdeghini EM, Di
Sacco S, Salvadori PA, Bevilacqua G, Adelstein SJ, Mosca F, Kassis AI. Tumor
targeting in vivo and metabolic fate of 5-[iodine-125]iodo-2'-deoxyuridine
following intratumoral injection in patients with colorectal cancer. J Nucl Med
1993; 34:1175-83.
Makrigiorgos GM, Baranowska-Kortylewicz J, Bump E,
Sahu SK, Berman RM, Kassis AI. A method for detection of
hydroxyl radicals in the vicinity of biomolecules using radiation-induced
fluorescence of coumarin. Int J Radiat Biol 1993;
63:445-58.
Kinsey BM, Kassis AI. Synthesis and
biological activity of 125I/127I-phenylboronic acid
derivatives. Nucl Med Biol 1993; 20:13-22.
Mariani G, Cei A, Giuliani L, Baranowska-Kortylewicz
J, Collecchi P, Di Stefano R, Di Lucca L, Viacava P, D'Elia F, Guadagni A,
Meucci G, Salvadori PA, Van den Abbeele AD, Bevilacqua G, Mosca F, Adelstein
SJ, Kassis AI. Tumor targeting potential and metabolism of 5-[125I]iodo-2'-deoxyuridine injected intratumorally in patients
with gastrointestinal or breast cancers. J Nucl Biol Med 1992; 36:154-7.
Van den Abbeele AD, Baranowska-Kortylewicz J,
Adelstein SJ, Carvalho PA, Tutrone RF, Richie JP, Wen PYC, Black PMcL, Mariani
G, Kassis AI. Diagnostic and therapeutic applications of
Auger-electron-emitting 5-[123I/125I]iodo-2'-deoxyuridine
in cancer. In: Howell RW, Narra VR, Sastry KSR, Rao DV, eds. Biophysical
aspects of Auger processes, Am Assoc Physicists Med Symp Proceedings No 8.
Nagasawa H, Kassis AI, Berman RM, Sahu SK, Nickoloff
JA, Okinaka RT, Adelstein SJ, Little JB. Comparison of mutation induction by
external and internal radiation sources in synchronized Chinese hamster ovary
(CHO) cells. In: Howell RW, Narra VR, Sastry KSR, Rao DV, eds. Biophysical
aspects of Auger processes, Am Assoc Physicists Med Symp Proceedings No 8.
Kassis AI. Editorial: The MIRD approach: remembering
the limitations. J Nucl Med 1992; 33:781-2.
Kassis AI, Adelstein SJ. Editorial: Does
nonuniformity of dose have implications for radiation protection? J Nucl Med
1992; 33:384-7.
Kassis AI. Dosimetric aspects of
administered radionuclides. In:
Muto MG,
Khawli LA, Kassis AI. m-[125I]iodoaniline: a
useful reagent for radiolabeling biotin. Nucl Med Biol 1992;
19:297-301.
Khawli LA, Van
den Abbeele AD, Kassis AI. N-(m-[125I]iodophenyl)maleimide: an agent for high yield
radiolabeling of antibodies. Nucl Med Biol 1992; 19:289-95.
Makrigiorgos GM, Berman RM, Baranowska-Kortylewicz J,
Bump E, Humm JL, Adelstein SJ, Kassis AI. DNA damage produced in V79 cells by
DNA-incorporated iodine-123: a comparison with iodine-125. Radiat
Res 1992; 129:309-14.
Kassis AI. Editorial: Optimizing antibodies for use
in nuclear medicine. J Nucl Med 1991; 32:1751-3.
Adelstein SJ, Kassis AI,
Baranowska-Kortylewicz J, Van den Abbeele AD, Mariani G, Ito S. Potential for
tumor therapy with iodine-125 labeled immunoglobulins. Nucl Med Biol
1991; 18:43-4.
Kassis AI, Guptill WE, Taube RA,
Adelstein SJ.
Radiotoxicity of 5-[125I]iodo-2'-deoxyuridine
in mammalian cells following treatment with 5-fluoro-2'-deoxyuridine. J Nucl
Biol Med 1991; 35:167-73.
Baranowska-Kortylewicz J,
Makrigiorgos GM, Van den Abbeele AD, Berman RM, Adelstein SJ, Kassis AI. 5-[123I]iodo-2'-deoxyuridine in the radiotherapy of an early
ascites tumor model. Int J Radiat Oncol Biol Phys 1991;
21:1541-51.
Van den Abbeele AD, Aaronson RA, Daher S, Taube RA,
Adelstein SJ, Kassis AI. Antigen-binding site protection during radiolabeling
leads to a higher immunoreactive fraction. J Nucl Med 1991; 32:116-22.
Mariani G, Ito S, Nayak RC, Baranowska-Kortylewicz J,
Venkateshan CN, Van den Abbeele AD, Eisenbarth GS, Adelstein SJ, Kassis AI.
Capping and internalization of monoclonal antibody-surface antigen complex: a
possible mode of interaction of monoclonal antibodies and tumor cells. J Nucl
Biol Med 1991; 35:111-9.
Tumeh SS, Carvalho PA, Van den
Abbeele AD, Maguire JH, Rauh DA, Neptune M, Kassis AI. Detection of
focal infection by 111In-human polyclonal IgG. J Nucl Biol
Med 1991; 35:4-9.
Janicek MJ, Van den Abbeele AD, DeSisto WC, Kassis
AI, Holman BL, Tumeh SS, Hollenberg NK. Embolization of platelets after endothelial
injury to the aorta in rabbits: assessment with 111indium-labeled
platelets and angiography. Invest Radiol 1991; 26:655-9.
Mariani G, Kassis AI, Adelstein SJ. Antibody
internalization by tumor cells: implications for tumor diagnosis and therapy. J Nucl Med Allied Sci 1990; 34:51-5.
Kassis AI, Makrigiorgos GM, Adelstein SJ. Dosimetric considerations and therapeutic potential of Auger
electron emitters. In: Adelstein SJ, Kassis AI, Burt RW, eds. Frontiers
in nuclear medicine: dosimetry of administered radionuclides, proceedings of
symposium, Washington, DC, 1989.
Makrigiorgos
GM, Adelstein SJ, Kassis AI. Limitations of MIRD at the cellular level. In: Adelstein SJ, Kassis AI, Burt
RW, eds. Frontiers in nuclear medicine: dosimetry of administered
radionuclides, proceedings of symposium,
Adelstein SJ,
Kassis AI. Preface. In: Adelstein SJ, Kassis AI, Burt RW, eds. Frontiers in nuclear medicine:
dosimetry of administered radionuclides, proceedings of symposium,
Kassis AI. 5-(123I/125I)iodo-2'-deoxyuridine for cancer diagnosis and therapy. J Nucl Med Allied Sci 1990; 34:299-303.
Makrigiorgos G, Adelstein SJ, Kassis AI. Auger
electron emitters: insights gained from in vitro experiments. Radiat Environ
Biophys 1990; 29:75-91.
Van den Abbeele
AD, Aaronson RA, Taube RA, Adelstein SJ, Kassis AI. Preadsorption of radiolabeled
monoclonal antibodies to liver and spleen tissues leads to higher
tumor-to-normal-tissue ratios. J Nucl Med Allied Sci 1990;
34:94-102.
Whaley JM, Kassis AI, Kinsey BM,
Adelstein SJ, Little JB. Mutation induction by 125iodoacetylproflavine,
a DNA-intercalating agent, in human cells. Int J
Radiat Biol 1990; 57:1087-103.
Muto GM, Finkler NJ, Kassis AI, Lepisto EM, Knapp RC.
Human anti-murine antibody responses in ovarian cancer
patients undergoing radioimmunotherapy with the murine monoclonal antibody
OC-125. Gynecol Oncol 1990; 38:244-8.
Makrigiorgos
GM, Baranowska-Kortylewicz J, Van den Abbeele AD, Ito S, Vinter DW, Adelstein
SJ, Kassis AI. Microscopic
spatial inhomogeneity of radiopharmaceutical deposition in mammalian tissues:
dosimetry at the cellular level and comparison with conventional dosimetry. Radiat Prot Dosimetry 1990; 31:319-24.
Makrigiorgos GM, Waker AJ, Kassis AI. Microdosimetric
characterisation of radiation fields with a high pressure ionisation chamber: a
comparison with the low pressure proportional counter. Radiat Prot
Dosimetry 1990; 31:161-5.
Makrigiorgos
GM, Ito S, Baranowska-Kortylewicz J, Vinter DW, Iqbal A, Van den Abbeele AD,
Adelstein SJ, Kassis AI. Inhomogeneous
deposition of radiopharmaceuticals at the cellular level: experimental evidence
and dosimetric implications. J Nucl Med 1990; 31:1358-63.
Makrigiorgos
GM, Adelstein SJ, Kassis AI. Cellular radiation dosimetry and its implications for
estimation of radiation risks. Illustrative results with technetium 99m-labeled
microspheres and macroaggregates. JAMA 1990; 264:592-5.
Livni E, Ito S, Kassis AI,
Kinsey BM, Fayad F, Venkateshan CN, Adelstein SJ,
Kassis AI. Synthesis and biological activity of the intercalating agent
3-acetamido-5-[123/125I]iodo-6-aminoacridine.
Nucl Med Biol 1990; 17:341-6.
Kassis AI, Van den Abbeele AD, Wen PYC, Baranowska-Kortylewicz
J, Aaronson RA, DeSisto WC, Lampson LA, Black PMcL, Adelstein SJ. Specific
uptake of the Auger electron-emitting thymidine analogue 5-[123I/125I]iodo-2'-deoxyuridine in rat brain tumors: diagnostic and
therapeutic implications in humans. Cancer Res 1990;
50:5199-203.
Kassis AI, Makrigiorgos GM, Adelstein SJ.
Implications of radiobiological and dosimetric studies of DNA-incorporated 123I:
the use of the Auger effect as a biological probe at the nanometre level. Radiat Prot Dosimetry 1990; 31:333-8.
Janicek MJ, Van den Abbeele AD, Hollenberg NK, Kassis
AI, Holman BL, Tumeh SS. Platelet activation and aggregation after endothelial
injury: assessment with indium-111-labeled platelets and angiography. Invest
Radiol 1990; 25:988-93.
Baranowska-Kortylewicz J, Berman RM,
Kaldany A, Eisenbarth GS, Kassis AI. Immunoradiometric assay for antibodies
recognizing antigenic gangliosides. J Nucl Med Allied
Sci 1990; 34:34-41.
Baranowska-Kortylewicz J, Adelstein
SJ, Kassis AI.
5-Iodo-2'-deoxyuridine-protein conjugates: synthesis and enzymatic degradation.
Sel Cancer Ther 1990; 6:1-13.
Mariani G, Van den Abbeele AD, Venkateshan CN,
Kaldany A, Ito S, Adelstein SJ, Kassis AI. Internalization of
monoclonal 3G5-IgM by a rat insulinoma cell line. Nuklearmedizin 1989;
Suppl 25:602-5.
Adelstein SJ, Kassis AI. Radiobiology
of alpha particle and Auger electron emitters. In: DeNardo GL, Lewis JP,
Raventos A, Burt RW, eds. Frontiers in nuclear medicine: biology of
radionuclide therapy, proceedings of symposium,
Weber DA, Eckerman KF, Dillman LT, Ryman JC, in
collaboration with Atkins HL, Budinger TF, Kassis AI, Lathrop KA, Loevinger R,
Marcus CS, Poston JW, Robertson JS, Siegel JA, Thomas SR, Watson EE. MIRD:
radionuclide data and decay schemes.
Muto MG,
Lepisto EM, Van den Abbeele AD, Knapp RC, Kassis AI. Influence of human antimurine
antibody on CA 125 levels in patients with ovarian cancer undergoing
radioimmunotherapy or immunoscintigraphy with murine monoclonal antibody OC 125.
Am J Obstet Gynecol 1989; 161:1206-12.
Makrigiorgos GM, Waker AJ, Kassis AI. Use of high pressure ionisation chambers and a comparison with
TEPCs for obtaining microdosimetric information in unspecified radiation
fields. Radiat Prot Dosimetry 1989; 29:15-9.
Makrigiorgos GM, Kassis AI, Baranowska-Kortylewicz J,
McElvany KD, Welch MJ, Sastry KSR, Adelstein SJ. Radiotoxicity of 5-[123I]iodo-2'-deoxyuridine in V79 cells: a comparison with 5-[125I]iodo-2'-deoxyuridine.
Radiat Res 1989; 118:532-44.
Makrigiorgos GM, Adelstein SJ, Kassis AI. Limitations of conventional internal dosimetry at the cellular
level. J Nucl Med 1989; 30:1856-64.
Kinsey BM, Van
den Abbeele AD, Adelstein SJ, Kassis AI. Absence of preferential uptake of [125I]iododihydrorhodamine 123 by four human tumor xenografts. Cancer Res 1989; 49:5986-8.
Khawli LA, Kassis AI. Synthesis of 125I
labeled N-succinimidyl p-iodobenzoate for use in radiolabeling
antibodies. Nucl Med Biol 1989; 16:727-33.
Mariani G, Van den Abbeele AD, Venkateshan CN,
Kaldany A, Ito S, Adelstein SJ, Kassis AI. Monoclonal antibody internalization
by tumor cells: an experimental model for potential radioimmunotherapy
applications. Nucl Med Biol 1989; 16:147-50.
Kassis AI, Fayad F, Kinsey BM, Sastry KSR, Adelstein
SJ. Radiotoxicity of an 125I-labeled DNA
intercalator in mammalian cells. Radiat Res 1989; 118:283-94.
Sastry KSR, Howell RW, Rao DV, Mylavarapu VB, Kassis
AI, Adelstein SJ, Wright HA, Hamm RN, Turner JE. Dosimetry of Auger emitters:
physical and phenomenological approaches. In: Baverstock KF,
Kassis AI, Howell RW, Sastry KSR, Adelstein SJ.
Positional effects of Auger decays in mammalian cells in culture. In:
Baverstock KF,
Adelstein SJ, Kassis AI. Criteria
for the selection of nuclides for radioimmunotherapy. In: Srivastava SC,
ed. Radiolabeled monoclonal antibodies for imaging and therapy, Proceedings of
the NATO Advanced Study Inst, Radiolabeled monoclonal antibodies for imaging
and therapy: potential, problems and prospects, Castelvecchio Pascoli, Italy,
1986.
Van den Abbeele
AD, Aaronson RA, Adelstein SJ, Kassis AI. Does the in vitro
testing of the immunoreactivity of an antibody reflect its in vivo behavior? J Nucl Med Allied Sci 1988;
32:260-7.
Macklis RM, Kinsey BM, Kassis AI,
Macklis RM, Kaplan WD,
Kinsey BM, Macklis RM,
Kassis AI, Kinsey BM. Iodo-reduced rhodamine 123.
Drugs Future 1988; 13:825-8.
Baranowska-Kortylewicz J, Kinsey BM,
Layne WW, Kassis AI. Radioiododemercuration: a simple synthesis of 5-[123/125/127I]iodo-2'-deoxyuridine.
Appl Radiat Isot 1988; 39:335-41.
Adelstein SJ, Kassis AI. Radiobiologic
implications of the microscopic distribution of energy from radionuclides.
Nucl Med Biol 1987; 14:165-9.
Kassis AI, Adelstein SJ, Bloomer WD.
Therapeutic implications of Auger-emitting radionuclides. In: Spencer RP, Seevers RH Jr,
Friedman AM, eds. Radionuclides in therapy.
Layne WW,
Kassis AI, Van den Abbeele A, Kinsey BM, Adelstein SJ. HPLC analysis of
the dissociation and recombination of rabbit immunoglobulin G. J Immunol
Methods 1987; 96:195-9.
Kinsey BM, Kassis AI, Fayad F, Layne WW, Adelstein
SJ. Synthesis and biological studies of iodinated (127/125I)
derivatives of rhodamine 123. J Med Chem 1987;
30:1757-61.
Kassis AI, Taube RA. Efficient
radiolabeling of mammalian cells using 111In-tagged liposomes.
Nucl Med Biol 1987; 14:33-5.
Kassis AI, Fayad F, Kinsey BM, Sastry KSR, Taube RA,
Adelstein SJ. Radiotoxicity of 125I in mammalian
cells. Radiat Res 1987; 111:305-18.
Kassis AI, Sastry KSR, Adelstein SJ. Kinetics of
uptake, retention, and radiotoxicity of 125IUdR in mammalian cells:
implications of localized energy deposition by Auger processes. Radiat Res 1987; 109:78-89.
Adelstein SJ, Kassis AI, Sastry KSR. Cellular vs.
organ approaches to dose estimates. In: Schlafke-Stelson AT, Watson EE, eds. In: Proceedings Fourth Int Radiopharm Dosimetry Symp,
Oak Ridge, TN, 1985, CONF-85113-(DE86010102).
Adelstein SJ, Bloomer WD, Kassis AI, Sastry KSR. The potential use of alpha and Auger-electron emitting
radionuclides for therapy. In: Winkler C, ed. Nuclear medicine in
clinical oncology.
Kassis AI,
Harris CR, Adelstein SJ, Ruth TJ, Lambrecht R, Wolf AP. The in vitro radiobiology of astatine-211
decay. Radiat Res 1986; 105:27-36.
Huberman MS, Lokich JJ, Hill T, Kaldany A, Kassis A,
Price T, Moore C, Davis S, Kasulis P, Monaco AP,
Haagensen DE Jr. Non-human primate (baboon) anti-carcinoembryonic antigen
antibody infusion in patients with metastatic adenocarcinoma: a phase I study. Cancer Immunol Immunother 1986; 23:137-42.
Kassis AI, Sastry KSR, Adelstein SJ. Intracellular
localisation of Auger electron emitters: biophysical dosimetry. Radiat Prot Dosimetry 1985; 13:233-6.
Kassis AI, Adelstein SJ. Chemotoxicity
of indium-111 oxine in mammalian cells. J Nucl Med 1985; 26:187-90.
Kassis AI, Sastry KSR, Adelstein SJ. Intracellular
distribution and radiotoxicity of chromium-51 in mammalian cells:
Auger-electron dosimetry. J Nucl Med 1985; 26:59-67.
Jones AG, Abrams MJ, Davison A, Brodack JW, Toothaker
AK, Adelstein SJ, Kassis AI. Biological studies of a new class of technetium
complexes: the hexakis(alkylisonitrile)technetium(I)
cations. Int J Nucl Med Biol 1984; 11:225-34.
Kassis AI, Adelstein SJ, Haydock C, Sastry KSR,
McElvany KD, Welch MJ. Radiotoxicity of Auger electrons in the DNA of mammalian
cells: a comparison of 123I with 125I and 77Br.
In: Broese JJ, Barendsen GW, Kal HB, Van der Kogel AJ, eds. Proceedings Seventh Int Congr Radiat
Res, Session E, Dosimetry, radionuclides and technology. Amsterdam:
Martinus Nijhoff Publishers, 1983:E5-07.
Kassis AI,
Adelstein SJ, Haydock C, Sastry KSR. Thallium-201: an experimental and a theoretical
radiobiological approach to dosimetry. J Nucl Med 1983; 24:1164-75.
Kassis AI,
Adelstein SJ, Wolf AP, Fowler JG, Shiue C-Y. Transient toxicity of 2-deoxy-2-[18F]fluoro-D-glucose in mammalian cells: concise
communication. J Nucl Med 1983; 24:1055-9.
Kassis AI, Adelstein SJ, Haydock C, Sastry KSR,
McElvany KD, Welch MJ. Lethality of Auger electrons from the
decay of bromine-77 in the DNA of mammalian cells. Radiat Res
1982; 90:362-73.
Kassis AI,
Adelstein SJ, Haydock C, Sastry KSR. Radiotoxicity of 75Se and 35S: theory
and application to a cellular model. Radiat Res 1980;
84:407-25.
Kassis AI, Adelstein SJ. A rapid
and reproducible method for the separation of cells from radioactive media.
J Nucl Med 1980; 21:88-90.
Kassis AI,
Warren KS, Mahmoud AAF. Antibody-dependent
complement-mediated killing of schistosomula in intraperitoneal diffusion
chambers in mice. J Immunol 1979; 123:1659-62.
Kassis AI, Warren KS, Mahmoud AAF. The Schistosoma haematobium egg granuloma.
Cell Immunol 1978; 38:310-8.
Kassis AI, Aikawa M, Mahmoud AAF. Mouse
antibody-dependent eosinophil and macrophage cell adherence and damage to
schistosomula of Schistosoma mansoni.
J Immunol 1978; 122:398-405.
Kassis AI,
Tanner CE. Echinococcus multilocularis: complement's role in vivo in hydatid disease. Exp Parasitol 1977; 43:390-5.
Kassis AI,
Tanner CE. Host serum proteins in Echinococcus
multilocularis: activation via the classical complement pathway. Immunology 1977;
33:1-9.
Kassis AI,
Tanner CE. Novel approach to the treatment of hydatid disease. Nature 1976;
262:588-9.
Kassis AI, Goh SL, Tanner CE. Lesions induced by
complement in vitro on the protoscoleces
of Echinococcus multilocularis: a
study by electron microscopy. Int J Parasitol 1976;
6:199-211.
Kassis AI, Tanner CE. The role of complement in
hydatid disease: in vitro studies. Int J Parasitol 1976; 6:25-35.
Kassis AI, Frayha GJ. Lipids of the
cysticerci of Taenia hydatigena
(Cestoda). Comp Biochem Physiol 1973; 46B:435-43.